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Cannabinoids & Fibromyalgia

Posted by Lewis Olden on
Cannabinoids & Fibromyalgia

Fibromyalgia is a chronic condition characterised by widespread musculoskeletal pain, fatigue, cognitive difficulties, and sleep disturbances. Treatments for fibromyalgia are limited, with many patients relying on lifestyle modifications and medications to manage their symptoms. However, there is growing evidence that cannabinoids may be a promising treatment for fibromyalgia.

What are cannabinoids? 

Cannabinoids are compounds derived from the Cannabis sativa plant, or marijuana. These compounds interact with the body’s endocannabinoid system, which plays a role in regulating pain, inflammation, mood, and sleep. Several studies suggest that cannabinoids may reduce the pain associated with fibromyalgia and improve sleep quality.

How can CBD help fibromyalgia? 

One study found that a combination of the cannabinoid cannabidiol (CBD) and tetrahydrocannabinol (THC) reduced pain in patients with fibromyalgia. Participants in the study reported a significant reduction in pain intensity, fatigue, and anxiety. Another study found that CBD reduced levels of cytokines, which are molecules that are associated with inflammation and pain.

In addition to reducing pain and inflammation, cannabinoids may also help improve sleep quality in fibromyalgia patients. Studies have found that cannabinoids can improve sleep quality, reduce the number of times someone wakes up during the night, and reduce the time it takes to fall asleep.

The benefits of cannabinoids for fibromyalgia may extend beyond pain and sleep. Cannabinoids have been shown to reduce stress, anxiety, and depression, all of which are common in fibromyalgia patients. A study found that CBD reduced levels of cortisol, a hormone associated with stress, in fibromyalgia patients.


The safety and efficacy of cannabinoids for fibromyalgia still need to be evaluated in larger, long-term studies. However, the current evidence suggests that cannabinoids may be a promising treatment option for fibromyalgia patients. In addition to reducing pain and improving sleep, cannabinoids may also reduce stress, anxiety, and depression. If you are considering using cannabinoids to treat fibromyalgia, it is important to talk to your doctor first to ensure that you are using a safe and effective treatment.

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